lnvthinh12 Spinebot's answer is correct! Although we do not provide specialized tools for using skeletons created with Spine as Vtubers, some users have already created their own tools for this purpose, and it is possible to create Vtuber avatars.
That said, in terms of whether it is possible to easily import skeleton data exported from Spine into commonly used tools for Vtubing, such as VTube Studio, this is not currently possible.
By the way, while the features in 4.2 are great, the Sliders and improved transform constraints added in 4.3-beta are also very useful for creating avatars for Vtubing, so please give them a try!