Creating empty skins in Spine is generally safe and can be useful for organizing your project, especially when using a multiple skin system. An empty skin acts as a placeholder and doesn't contain any attachments, which means it won't affect performance or cause issues during runtime. However, it's important to note that if a skin is set to null or an attachment cannot be found in the skin, the skeleton will look in the SkeletonData's default skin for attachments. This behavior ensures that your skeleton can still display attachments even if an empty skin is applied. Therefore, using empty skins is a valid approach and should not pose any significant risks to your project.